Ok guys had enough thyroid yet? Well then Vote what to do next week!
Well guess what today you get 3 cases!!
7. 68 yo woman with a rapidly enlarging neck mass
http://bit.ly/1gi17Ge
8. 50 yo Female with thyroid nodule, cold on radio-isotope scan
http://bit.ly/1brEx6n
9. 25 yo with family history of thyroid cancer
http://bit.ly/1eqLOEl
7) Anaplastic (undifferentiated) carcinoma - Comes in 3 flavors and all are terrible for the patient a. Epithelioid, b. spindle c. Giant cell, all are ugly and all are BAD!
ReplyDelete8) ok credit goes to all those that wrote Fol variant of PTC eventhough the rosai collection has this listed as follicular carcinoma. I think there are significant nuclear changes towards PTC which either cannot be ignored or the virtual slide just doesnt let us see close enough
9)This is medullary thyroid Ca - tumor of the "c" cells (the cells Hurthle actually described it was Askenazy who described what we now call the Hurthle cell!) ~20% are familial, ass with mutations in RET. endocrine nuclear features (can look like a lot!) may have stromal amyloid (this case) and will be calcitonin +